Rapid carbonylative coupling reactions using palladium(I) dimers: applications to 11CO-radiolabelling for the synthesis of PET tracers.
نویسندگان
چکیده
Palladium dimers with sterically hindered phosphines have been shown to be excellent pre-catalysts for the aminocarbonylation of aryl halides to yield amides and one of them has been successfully employed as a pre-catalyst for the synthesis of (11)C-radiolabelled amides for PET imaging.
منابع مشابه
Ultra - rapid carbonylation using palladium ( I ) dimer precatalysts applied to 11 CO - radiolabelling for PET
Palladium dimers with sterically hindered phosphines have been shown to be excellent precatalyst for the aminocarbonylation reaction of aryl halides to yield amides. Two particularly relevant features of some of these catalytic systems are that they operate at atmospheric pressure of CO and that they give high yields of the corresponding amide within very short periods of time (under 10 minutes...
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 9 شماره
صفحات -
تاریخ انتشار 2011